Melatonin 6 hour time -triggered release - 750 mcg, 60 vegetarian tablets

Description: Melatonin is a natural hormone that promotes sleep by regulating the body's circadian rhythm. It is known to contribute to faster sleep, but also has a number of health benefits beyond sleep quality. This addition gives a low dose (750 mcg) melatonin that is gradually released over a period of six hours, which helps to both fall asleep and stay asleep through the night. The time -regulated liberation ensures stable levels of melatonin in the body, which can be especially useful for those who experience occasional insomnia or have difficulty maintaining a good circadian rhythm.

Benefits and Effects:

• Promotes optimal sleep quality: This formulation ensures a gradual release of melatonin over six hours, which helps to improve both the duration of sleep and the duration of sleep.
• Supports healthy circadian rhythm: Melatonin helps regulate the body's natural sleep-wet cycle, and can be useful for people affected by jet lag, shift work or age-related reduction in melatonin production.
• Strengthens the immune system: Research has shown that melatonin supports the immune system by promoting a balanced immune response.
• Protects from oxidative stress: Melatonin acts as a powerful antioxidant, which helps protect the cells' DNA and mitochondria from damage caused by free radicals.
• Supports cognitive health: Melatonin has been shown to support healthy brain function and can promote cognitive health, especially in old age.

How does melatonin work? Melatonin is naturally produced in the pineal gland from the amino acid tryptophan, with main production at night when it is dark. Melatonin production decreases with age and is affected by exposure to light in the evening, which can interfere with the body's natural sleep pattern. Supplements of melatonin help restore normal circadian rhythm, promote sleep and improve sleep quality.

Melatonin and sleep: Good sleep is essential for general health and well -being. Melatonin plays a key role in promoting sleep by signaling to the body that it is time for rest. Studies have shown that supplementation of melatonin can contribute to better sleep, especially in people with disturbed sleep patterns.

Melatonin and oxidative stress: Melatonin is also known for its powerful antioxidant properties. It helps to inhibit oxidative damage to the cells, and it has been found to be more effective than many other antioxidants in protecting cellular DNA and mitochondria from injury.

Melatonin and the immune system: Melatonin can also help modulate the immune system by stimulating immune response when necessary and attenuating overactive reactions. This makes melatonin an effective supporter of immune health.

Ingredients:

• Melatonin (750 mcg per tablet)
• Microcrystalline cellulose
• Hypromellosis
• Water -soluble dragging (purified water, hydromellosis, glycerin)
• Candle
• Vegetable Stearat
• Sodium-Carboxymethyl cellulose (E466)
• Silicon dioxide (SiO2)

Dosage and use: Take one (1) tablet 30 to 60 minutes before bedtime, or as recommended by health professionals. For the best effect, melatonin should be taken in the evening when the body naturally begins to produce the hormone.

Precautions:

• Contact your doctor before use if you are treated for a medical condition (especially autoimmune or depressive disorders).
• Avoid alcohol when consuming melatonin.
• Not recommended for children, pregnant or lactating women.
• Do not drive or operate heavy machines after taking melatonin.
• Keep out of reach of children.
• Do not exceed the recommended dosage.

Disclaimer: This product is not intended to diagnose, treat, cure or prevent illness. All use of supplements takes place at your own responsibility and should be done in consultation with a doctor. Recommended daily dose should not be exceeded. Supplements should not replace a varied diet. Keep out of reach of children. Uno Vita AS does not claim that the products we market can cure disease. The information here is only intended as guidance and is not a substitute for professional medical advice.

Freedom of speech and right to information: Uno Vita reserves the right to share publicly available research and information on health and wellness technologies, natural substances, vitamins and the like. We do this with reference to national and international laws on freedom of speech.

References:

1. Reiter RJ, Tan DX, et al. "Melatonin as an antioxidant: biochemical mechanisms and pathophysiological implications in human." Acta biochimica polonica. 2007.
2. Galano A, Tan DX, Reiter Rj. "On the Free Radical Scavenging Activities of Melatonin's Metabolites, AFMK and Amk." Journal of Pineal Research. 2013.
3. Hardeland R. "Melatonin and the Theories of Aging: A Critical Appraisal of Melatonin's Role in Anti-Aging Processes." Journal of Pineal Research. 2012.
4. Carrillo-Vico A, Lardone PJ, et al. "Melatonin's Dual Role as An Anti-Inflammatory and Antioxidant in the Aging Brain." Neuroscience Letters. 2013.
5. Cardinali DP, et al. "Melatonin Effects on Immune Responses: Its Role in Diseases and as A Therapeutic Agent." Journal of Pineal Research. 2003.
6. Acuña-Castroviejo D, et al. "Melatonin-Mitochondria Interplay in Health and Disease." Current Topics in Medicinal Chemistry. 2011.
7. Pandi-Perumal SR, et al. "Role of melatonin in the regulation of human circadian rhythms and sleep." Journal of Pineal Research. 2007.
8. Claustrat B, Brun J, et al. "Melatonin and aging: Physiological and therapeutic perspectives." Neuroendocrinology Letters. 2005.
9. Zisapel N. "Melatonin-Dopamine Interactions: From Basic Neurochemistry to A Clinical Setting." Progress in Neurobiology. 2010.
10. Reiter RJ, et al. "Melatonin AS an anti-aging, antioxidant and anti-inflammatory agent." Endocrine journal. 2008.
11. Videnovic A, et al. "Circadian and sleep dysfunction in neurodegenerative disorders: Role of melatonin." Journal of Clinical Sleep Medicine. 2014.
12. Korkmaz A, Reiter RJ, et al. "Melatonin and cognitive function in the elderly." Journal of Clinical Sleep Medicine. 2011.