Magnesium glycinate: Science and health effects

Summary
Magnesium glycinate, also known as magnesium bisglysinat, is a high bioavailable form of magnesium that combines this essential mineral with the amino acid glycine. This chelated compound is designed to provide very good absorption in the body and minimal load on the digestive system, which sets it apart from other magnesium forms such as magnesium oxide or magnesium sitrat. Magnesium is crucial for a variety of physiological processes, including energy production, muscle and nerve function, and maintenance of bone health. Magnesium glyate has become a popular dietary supplement for people who want to support the body's natural functions in a gentle and efficient way. This article provides a detailed overview of the product's characteristics, benefits and technical specifications, based on available research and scientific data, without making medical claims about the prevention or treatment of diseases.

Benefits and effects
Magnesium glyate offers a variety of documented benefits that support the body's natural processes and general well -being. These effects are based on the role of the magnesium in human physiology and the supplementary properties of the glycine such as amino acid. Here is a comprehensive review of the main benefits presented as Bulletpoints:

• Muscle function and relaxation: Magnesium helps maintain normal muscle function, essential for daily movement and physical activity, and supports muscle relaxation, which can be useful after exercise or by physical exertion. Glycine reinforces this effect with its soothing effect on the nervous system.
• Energy turnover and ATP production: Magnesium plays a key role in the conversion of nutrients into ATP, the primary energy source of the cells, and supports a stable energy supply throughout the day, which is valuable for an active lifestyle.
• Nerve function and stress management: Magnesium supports normal functioning of the nervous system by regulating neurotransmitters such as serotonin and gaba, and along with glycine it can promote a balanced nerve function and a sense of inner calm, positive for sleep quality and stress management.
• Bone health and mineralization: Magnesium helps maintain normal bones by supporting bone mineralization and collaborating with calcium and vitamin D, which is relevant to maintaining bone strength of all ages.
• Heart health and blood pressure control: Magnesium supports normal muscle function in the heart and maintaining blood pressure levels within the body's natural framework by regulating ion channels that affect the heartbeat.
• Blood sugar regulation: Magnesium is involved in carbohydrate metabolism and insulin activity, and contributes to normal blood sugar regulation, a support for maintaining stable blood sugar levels in a healthy lifestyle.
• Hormonal balance: Magnesium glycate can reduce discomfort such as bloating or muscle tension before menstruation through muscle relaxation and the soothing properties of the glycon, and supports a sense of physical and emotional balance.
• Oxidative stress and antioxidant properties: Magnesium protects the cells from oxidative stress by activating enzymes that neutralize free radicals, a natural part of the body's defense system that supports general cell health.
• Physical achievement and recovery: Magnesium supports the efficiency of the muscle during activity and contributes to recovery after training by maintaining the electrolyte balance and reducing muscle stiffness, useful for athletes and active individuals.

These benefits are in line with approved EFSA health claims, which "magnesium contributes to normal muscle function," "magnesium helps to normal energy conversion," and "magnesium helps maintain normal bones." Magnesium glyate stands out by delivering these effects in a gentle and very well absorbed way.

Technical specifications
Magnesium glycinate is a chelated compound consisting of one magnesium atom bound to two molecules of glycine, a non-essential amino acid. This chemical structure, often referred to as magnesium bisglysinat, provides the product unique properties that set it apart from other magnesium supplements. The molecular formula for magnesium glycinate is Mg (c2h4no2) 2, with a molar mass of about 172.43 g/mol. The chelatization means that the magnesium ion is surrounded by the glycine molecules, which creates a stable ring structure. This bond protects the magnesium from reacting too early in the stomach acid environment and increases its absorption in the small intestine, where absorption primarily occurs. Studies have shown that chelated forms of magnesium, such as glycate, have a high bioavailability that exceeds unnoticed forms such as magnesium oxide, which are often only absorbed to a limited extent due to low solubility. Magnesium glyate also has good water solubility, which further improves the absorption of the gastrointestinal system. When magnesium glycate is consumed, it is dissocated to magnesium ions (mg²⁺) and free glycine molecules. The magnesium ions are then transported into the bloodstream and distributed to cells throughout the body, where they participate in enzymatic reactions such as energy production, protein synthesis, and regulation of muscle and nerve function. The glycine molecules can be absorbed separately and used in processes such as collagen production or act as a neurotransmitter in the central nervous system. The product is typically available in capsule or powder form, with magnesium content that varies depending on the manufacturer. A capsule can contain 100–200 mg elementary magnesium, and Common recommended dosage varies from 200 mg to 400 mg per day, depending on individual needs and health status. Magnesium glyate is known for its low risk of gastrointestinal side effects, thanks to the chelated structure and glycine's neutral pH. The stability of the product ensures that the magnesium content remains intact over time. The recommended daily intake of magnesium is 400–420 mg for adult men, 310–320 mg for women, and 350–400 mg for pregnant or breastfeeding, with a tolerable upper intake level of 350 mg from supplementation.

Comprehensive and detailed description
Magnesium glyate is a result of many years of research on mineral absorption and human physiology, and represents one of the most advanced forms of magnesium supplements. Magnesium is the fourth most widespread mineral in the body and is found in high concentration in bones, muscles and soft tissue. It is a cofactor in over 300 enzyme systems, including those who control glucose metabolism, fat burning and DNA replication. Without adequate magnesium, these processes can become ineffective, which emphasizes the importance of adequate levels through diet or supplementation such as magnesium glycinate. Magnesium regulates calcium channels in muscle and nerve cells, and magnesium glycate helps to restore the balance by adding magnesium quickly and efficiently, enhanced by the soothing effect of the glycerin. Glycine binds to receptors in the brain that inhibits neuronal activity, which may explain reports of relaxation and better sleep quality, especially when ingested in the evening. Glycine also supports collagen production, which contributes to skin, joints and bones. Magnesium collaborates with calcium and phosphorus to form hydroxyapatitis in bones, activates osteoblasts and inhibits osteoclasts, which is crucial to bone strength. In the heart, the magnesium sodium-potassium pump and promotes vasodilatation, a natural part of cardiovascular health. Magnesium supports insulin sensitivity and glucose uptake, which may be an advantage for a healthy metabolism. For women, magnesium glycate reduces hormonal discomfort through muscle relaxation and neurotransmitter balance. During training, magnesium regulates electrolytes and reduces lactic acid structure, which supports performance and recovery. Magnesium protects the cells from oxidative stress by activating enzymes as super oxiddismutase (SOD). The product is versatile and can be taken daily or in specific situations, and can be combined with vitamin B6 to enhance nervous system support. Natural sources such as spinach, almonds and salmon complement magnesium glycinate, but the supplement ensures adequate intake for increased need. Dosage of 100-300 mg daily is common, and the product contains no fillers or allergens. The chelated binding increases the absorption of the small intestine, and magnesium glycinate also supports inflammation balance through cytokin regulation. It fits a wide range of users and is gentle even for sensitive stomachs.

Disclaimer and reservation
Magnesium glyate is a dietary supplement intended to support general health and well -being. It is not intended to diagnose, treat, cure or prevent any kind of illness. Uno Vita AS does not claim that this product can replace medical treatment or solve specific health conditions. People with existing medical conditions, such as kidney disease or other serious health problems, or those taking medications that may be affected by magnesium, should consult qualified health professionals before use. Pregnant and breastfeeding women should also consult a doctor. The product should be kept inaccessible to children and used according to the recommended dosage to avoid side effects such as loose stomach or nausea for excessive intake. The use of magnesium supplements should be done in consultation with qualified health professionals.

Freedom of speech and right to information
UNO Vita AS reserves the right to share publicly available research on health and wellness technologies, including magnesium glycate, in accordance with international principles of freedom of speech and information sharing. This is in line with the UN Human Rights (1948), Article 19, the International Convention on Civil and Political Rights (1966), Article 19, Norwegian Constitution Section 100, and the US First Amendment. Our goal is to provide consumers balanced and research -based information for informed choices about health and lifestyle.

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