Introduction Coenzyme Q10, also known as CoQ10, is a fat-soluble substance found naturally in almost all cells of the body. Similar to a vitamin, this molecule plays a crucial role in the body's energy production and has powerful antioxidant properties that protect cells from damage caused by oxidative stress. Although the body itself produces CoQ10, levels naturally decrease with age and in certain health conditions, making it important to ensure adequate amounts through diet or supplementation for optimal health.

CoQ10 is found in particularly high concentration in organs with high energy requirements such as the heart, liver and kidneys, and works in the mitochondria - the power plant of the cells - where it helps convert nutrients into energy in the form of ATP (adenosine triphosphate). CoQ10's role as an antioxidant is also crucial, as it helps to neutralize free radicals that can otherwise cause cell damage, inflammation, and promote aging processes. CoQ10 has also been shown to support a number of functions, including cardiovascular health, energy metabolism, and liver function, as well as helping to reduce fatigue and strengthen the immune system.

Benefits and Health Effects of CoQ10
-
Cardiovascular health The heart has a high concentration of CoQ10, and this is because the heart depends on constant energy turnover to pump the blood around the body. Several clinical studies have shown that CoQ10 can help maintain normal heart function by reducing oxidative stress, which reduces the risk of cell damage and inflammation in the heart muscle. This may be particularly beneficial for people at risk of cardiovascular disease, as CoQ10 can help maintain normal cholesterol and blood pressure levels, and support healthy blood flow by promoting vasodilation, a process in which blood vessels widen.

-
Energy production and reduced fatigue CoQ10 plays a crucial role in energy production by being part of the mitochondria's electron transport chain, where it helps produce ATP – the body's most important energy source. This is important for both physical and mental performance, and research has shown that CoQ10 can reduce fatigue, especially after cognitive tasks. People who experience persistently low energy may benefit from supplementation with CoQ10, particularly since CoQ10 is necessary for the metabolism of fatty acids, which are an important source of energy for cells. Research has also suggested that CoQ10 can have a positive effect on cognitive function and endurance, helping to reduce feelings of fatigue and sleepiness after mental exertion.

-
Support for liver function CoQ10 has been shown to have a positive effect on liver function. Studies have shown that CoQ10 can help maintain normal levels of ALT, AST and GGT, which are liver enzyme levels that indicate the condition and health of the liver. CoQ10's antioxidant properties protect the liver against oxidative stress and can thus reduce the risk of liver damage. This can be particularly important for people with elevated liver values or who have been exposed to toxins that negatively affect liver function.

-
Antioxidant protection and inflammatory response CoQ10 acts as a powerful antioxidant and protects cells from oxidative stress, which can help to counteract inflammation in the body. Oxidative stress is a condition that occurs when the body produces more free radicals than it can handle, and this can lead to cell damage and accelerate the aging process. CoQ10 helps to neutralize free radicals, which can reduce the risk of inflammation and protect the body's cells. This can be beneficial for eye and skin health, as well as for people who want to counteract signs of aging such as wrinkles and loss of skin elasticity. In addition, it can reduce the risk of age-related diseases, such as cataracts.

-
Support for the immune system CoQ10 can also strengthen the immune system by protecting the immune cells from oxidative damage and helping to maintain a strong defense against infections and diseases. The immune cells are particularly sensitive to oxidative stress, and CoQ10's antioxidant properties provide protection against this process, which can strengthen the immune response and support the body's natural defenses against external influences.

-
Reduces aging processes One of the more documented benefits of CoQ10 is its role in reducing the signs of aging. As a result of its work in the mitochondria, CoQ10 helps keep cells energized and protects against DNA damage. Oxidative stress is one of the main causes of ageing, and by limiting this, CoQ10 can potentially delay visible signs of aging such as wrinkles, loss of skin firmness and elasticity, as well as preserve the cells' ability to function over time.
Technical specifications and recommendations for use
-
Form: CoQ10 supplements are available in two main forms, ubiquinone and ubiquinol. Ubiquinol is the reduced form of CoQ10 and is better absorbed in the body, and is therefore often recommended for elderly people or people with special needs. However, ubiquinone is a cost-effective alternative that still provides health benefits.
-
Recommended dosage: The daily dosage depends on the individual's health and needs. A typical daily dose is between 30 and 200 mg, but it is important to consult a healthcare professional to find the most appropriate dosage.
- Intake and admission: CoQ10 is a fat-soluble substance and should therefore be taken with food containing fat to optimize absorption. This can be a yoghurt, a salad with olive oil or fatty fish such as salmon. For people with a sensitive stomach, it is recommended to take the supplement after a meal to avoid stomach upset.
Recommendations for use and absorption
To maintain stable levels of CoQ10 in the body, it is recommended to take the supplement daily. It is beneficial to take it earlier in the day, as CoQ10 can have an invigorating effect. For best absorption, CoQ10 should be taken with a meal containing some fat, which can significantly increase bioavailability. This can be a snack with avocado, nuts or fish.
Dietary sources of CoQ10 Although it is difficult to meet the body's needs through diet alone, there are small amounts of CoQ10 in foods such as meat, fish, nuts and oils. Some dairy products, fruit, vegetables and grains also contain CoQ10, but the concentration in these foods is relatively low compared to supplements. To maintain sufficient levels in the body, supplements are therefore often recommended as a practical solution.
Conclusion Coenzyme Q10 is a versatile and powerful supplement with documented benefits for energy, cell protection and cardiovascular health. With its strong antioxidant properties, CoQ10 can reduce oxidative stress and strengthen the immune system, as well as support heart health and energy levels through an efficient turnover of nutrients in the cells. For people looking to promote overall health, energy and reduce the signs of aging, a supplement of CoQ10 can be a valuable addition to a balanced diet. Its contribution to reducing oxidative stress makes CoQ10 a recommended supplement especially for adults who want to maintain healthy cell functions over time.
Freedom of expression and right to information Uno Vita reserves the right to share publicly available research and information on health and wellness technologies, natural substances, vitamins and the like. We do this with reference to national and international laws on freedom of expression and belief, including:
- United Nations Universal Declaration of Human Rights (1948): Article 19 ensures the right to freedom of opinion and expression, including the freedom to receive and impart information regardless of frontiers.
- The International Covenant on Civil and Political Rights (1966): Article 19 emphasizes the right to freedom of expression and the freedom to seek, receive and impart information and ideas through various media.
- Norwegian Constitution § 100: Ensures freedom of expression, with certain limitations for reasons of child protection, privacy, public order and safety.
- America's First Amendment: Protects freedom of speech against government interference and provides one of the strongest protections for free speech. Uno Vita reserves the right to freedom of opinion and expression in line with these principles.
References
- Biswas SK. "Does the Interdependence between Oxidative Stress and Inflammation Explain the Antioxidant Paradox?" Oxidative Medicine and Cellular Longevity. 2016.
- Damaneh MS, et al. "The effect of coenzyme Q10 supplementation on liver enzymes." Food Sci Nutr. 2023.
- Drovandi S, et al. "Oral Coenzyme Q10 supplementation in steroid-resistant nephrotic syndrome." Clinical Investigation. 2022.
- Long YC, Zierath JR. "AMP-activated protein kinase signaling in metabolic regulation." J Clin Invest. 2006.
- Mizuno K, et al. "Ubiquinol-10 intake and fatigue relief in healthy individuals." Nutrients. 2020.
- Pravst I, et al. "Coenzyme Q10 contents in foods and fortification strategies." Crit Rev Food Sci Nutr. 2010.
- Rabanal-Ruiz Yoana, et al. "The Use of Coenzyme Q10 in Cardiovascular Diseases." Antioxidants (Basel). 2021.
- Saini R. "Coenzyme Q10: The essential nutrient." J Pharm Bioallied Sci. 2011.
- Yoo JY, Yum KS. "Effect of Coenzyme Q10 on Insulin Resistance in Korean Patients with Prediabetes." Biomed Res Int. 2018.
- "Antioxidant Supplements: What You Need to Know." NCCIH. 2023.
- "Antioxidants." Harvard T.H. Chan School of Public Health.
- "Coenzyme Q10." Oregon State University. 2018.