Gamma E Mixed Tocopherols & Tocotrienols – 60 softgels
Dietary supplement with complete vitamin E complex for antioxidant protection and cell health

Gamma E Mixed Tocopherols & Tocotrienols from Life Extension provides you with the full range of vitamin E compounds found naturally in plants: alpha, beta, gamma and delta tocopherols and tocotrienols. These eight related lipid-soluble compounds have complementary biological functions and play a key role in the protection of cell membranes, nerves and blood vessels against oxidative stress. This product has been developed for those who want broad antioxidant protection and support for heart, brain and cell function.

Health benefits
Vitamin E is an essential nutrient that helps protect cells against oxidative stress (EFSA ID 2806). The combination of tocopherols and tocotrienols provides a wider biological effect than conventional supplements containing only alpha-tocopherol.
• Contributes to protecting cells against oxidative stress.
• Supports normal function of the immune system.
• Contributes to maintaining normal blood vessel function and blood flow.
• Promotes normal nerve and brain signaling.
• Can contribute to the skin's protection against oxidative effects from sunlight and environmental factors.
• Helps support disc function and healthy microcirculation.
• Can promote a balanced inflammatory response through the neutralization of peroxy-nitrite radicals.

Top 2 main features

1. Advanced antioxidant protection: The vitamin E complex in the product neutralizes reactive oxygen and nitrogen compounds and helps protect cell membranes and DNA against oxidative degradation.

2. Support for the nervous and vascular system: The tocotrienols in the formula can help maintain elastic blood vessels, support healthy nerve conduction and protect the brain from oxidative stress.

A surprising or lesser known effect
Recent research shows that gamma-tocopherol is particularly effective at neutralizing peroxy-nitrite – a reactive free radical that can affect cell function during ageing. This form of vitamin E is often in short supply in the normal diet and therefore provides significant additional protection beyond alpha-tocopherol alone.

Technical details and specifications
• Vitamin E (from D-alpha-tocopherol): 30.15 mg
• Gamma E Mixed tocopherol/tocotrienol complex (with 374 mg mixed tocopherols, 56 mg mixed tocotrienols): 524 mg
Other ingredients: Gelatin (capsule), glycerin, medium chain triglycerides, purified water, sunflower oil, rosemary extract.
Free for: gluten, GMO, artificial color and flavor.

The tocotrienols are extracted from natural plant sources (such as palm fruit and rice bran), while the tocopherols come from natural vegetable oil.

Recommended use
Take one (1) soft capsule one to two times daily with food, or as recommended by a doctor or healthcare professional.

Label information
Dietary supplement with mixed vitamin E compounds (tocopherols and tocotrienols).
Contents per pack: 60 soft capsules.
Recommended daily dose: 1–2 capsules.
Store dry and protected from light.
Warning: People who use blood-thinning drugs or have bleeding disorders should consult a doctor before use.
Manufacturer: Life Extension, USA.
Importer and distributor: Uno Vita AS, Norway.

Reservation
Allowed to be used by adults. All use of supplements is at your own risk and should be done in consultation with a doctor. The recommended daily dose should not be exceeded. The effect of this product may vary from person to person. Dietary supplements should not replace a varied diet. Should be kept out of the reach of children. Uno Vita AS does not claim that the products we market can cure disease.

Disclaimer
Uno Vita increasingly uses artificial intelligence for analytical work and text production. We do not accept responsibility for errors or inaccuracies due to insufficient information or AI-generated deviations. The information is intended for general information and should not replace medical advice, diagnosis or treatment. Uno Vita disclaims all responsibility for loss or damage that may arise as a result of the use of information or products. Always consult your health care professional before starting a new treatment or supplement.

Freedom of expression and right to information
Uno Vita reserves the right to disseminate publicly available research on natural substances and health technologies, in line with the principles of freedom of expression in the UN Declaration of Human Rights (art. 19), ICCPR (art. 19), Norwegian Constitution §100 and the US First Amendment.

Scientific references

1. Brigelius-Flohé R et al. "Vitamin E: Function and Metabolism." FASEB J. 1999.

2. Traber MG et al. "Mechanisms for the selective retention of α-tocopherol in humans." J Lipid Res. 1999.

3. Packer L et al. "Vitamin E: Antioxidant activity and cell signaling." Free Radic Biol Med. 2001.

4. Late CK et al. "Tocotrienols: Vitamin E beyond tocopherols." Ann N Y Acad Sci. 2004.

5. Jiang Q et al. "Gamma-tocopherol and its major metabolite protect against nitrosative stress." PNAS. 2001.

6. Wolf G. “Gamma-tocopherol, a major form of vitamin E in the U.S. diet, deserves more attention.” J Nutr. 1997.

7. Stone WL et al. "Comparative antioxidant properties of tocopherols and tocotrienols." J Am Coll Nutr. 2003.

8. Qureshi AA et al. "Suppression of cholesterol synthesis by tocotrienols." J Biol Chem. 1986.

9. Theriault A et al. "Tocotrienol modulates lipid metabolism and protects arteries." Atherosclerosis. 1999.

10. Yuen KH et al. "Tocotrienol supplementation and lipid profile in humans." Nutr Res. 2011.

11. Late CK et al. “Neuroprotective actions of alpha-tocotrienol.” J Biol Chem. 2000.

12. Khanna S et al. "Alpha-tocotrienol protects neurons from glutamate-induced toxicity." J Neurochem. 2003.

13. Burton GW et al. "Vitamin E as an in vivo antioxidant." Ann N Y Acad Sci. 1989.

14. Brigelius-Flohé R, Kelly FJ. “Vitamin E and cellular signaling.” Biochem Biophys Res Commun. 2016.

15. Das S et al. "Tocotrienols and cell membrane integrity." Nutr Metab. 2012.

16. Leung YW et al. "Tocotrienols attenuate oxidative stress in endothelial cells." Free Radic Biol Med. 2009.

17. Makpol S et al. "Vitamin E and aging cells." Clin Interv Aging. 2011.

18. Huang J et al. "Tocotrienols in neurodegenerative diseases." Nutrients. 2018.

19. Yap SP et al. "Absorption and bioavailability of tocotrienols." Am J Clin Nutr. 2001.

20. Aggarwal BB et al. "Tocotrienols inhibit NF-κB signaling." Biochem Pharmacol. 2004.

21. Brigelius-Flohé R et al. "Emerging roles of vitamin E in cellular signaling and gene regulation." Mol Aspects Med. 2020.