Clove herbal extract tincture – overall product description

Summary Clove herbal extract tincture is a powerful liquid herbal extract made from dried flower buds of the clove tree (Syzygium aromaticum). This all-natural supplement is rich in eugenol and other bioactive compounds with documented antioxidants, anti-inflammatory, antimicrobial and antiparasitic properties. The product is made with a potent ratio of 1:3 between herb and menstruum (extraction liquid), and provides a concentrated form of clove's therapeutic properties. A 2oz (approx. 59ml) bottle provides a simple and effective way to support the body's natural defense and detoxification systems.

Top 2 main features and one surprising effect The most documented effects of clove tincture is its ability to protect cells from oxidative stress and help reduce inflammatory processes in the body. In addition, the product has been shown to support digestive function by stimulating enzymes and protecting mucous membranes. A lesser known but important effect is its antiparasitic effect, which can help cleanse the digestive system by weakening and inhibiting parasites.

Health benefits and mechanisms of action

1. Antioxidant effect
   Eugenol and polyphenols in cloves act as powerful antioxidants that neutralize free radicals and protect cell structures such as DNA, proteins and lipids. They also activate Nrf2, which stimulates the body's own antioxidant systems (including superoxide dismutase and glutathione peroxidase), as well as bind metal ions that otherwise catalyze the formation of reactive oxygen species (ROS).

2. Anti-inflammatory effect
   Eugenol inhibits pro-inflammatory enzymes such as COX-2 and lipoxygenase, and reduces levels of pro-inflammatory cytokines such as TNF-α, IL-1β and IL-6. It also affects intracellular signaling pathways such as NF-κB and MAPK and thus helps to reduce inflammation.

3. Antimicrobial activity
   Clove extract exerts an antimicrobial effect by disrupting the cell membrane of microorganisms, inhibiting microbial enzymes and preventing biofilm formation. This makes it useful for oral hygiene, skin care and support for the immune system.

4. Pain-relieving property
   Eugenol acts as a pain reliever by modulating voltage-gated sodium channels and reducing nerve excitability. This explains the traditional use against toothache and bodily discomfort.

5. Digestive support and mucosal protection
   Cloves stimulate the secretion of digestive enzymes and support intestinal motility. Its antioxidant and anti-inflammatory properties also protect the mucous membranes of the gastrointestinal tract.

6. Antiparasitic effect
   Clove extract exerts a broad-spectrum antiparasitic effect:

• Eugenol penetrates the cell membranes of parasites and leads to leakage and death

• Inhibits enzymatic processes important for the parasite's metabolism and energy production

• Induces oxidative stress in the parasite, which damages cell structures

• Disrupts reproductive cycles and prevents the development of eggs and larvae
  Studies have shown an effect against Giardia lamblia, Entamoeba histolytica, Ascaris lumbricoides, Schistosoma mansoni, Trypanosoma cruzi and Leishmaniaspecies.

7. Emerging systemic benefits
   Preclinical research suggests that clove extract can contribute to liver protection by reducing oxidative stress in liver cells. Furthermore, eugenol has shown potential to improve insulin sensitivity and lipid profile, which can have beneficial effects on blood sugar and heart health.

Technical specifications

• Volume: 2 oz (approx. 59 ml)

• Dosage: 30–50 drops (1.5–2.5 ml) in water or juice, 2–4 times daily between meals

• Extraction ratio: 1:3 herb/menstruum

• Quality: Made from dried cloves (Syzygium aromaticum), completely clean and naturally grown without pesticides

Reservation Allowed to be used by adults. All use of supplements is at your own risk and should be done in consultation with a doctor. The recommended daily dose should not be exceeded. The effect of this product may vary from person to person. Dietary supplements should not replace a varied diet. Should be kept out of the reach of children. Uno Vita AS does not claim that the products we market can cure disease.

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Scientific references

1. Chaieb K. et al. "Antibacterial activity of clove essential oil against bacteria isolated from burned patients". Ann Clin Microbiol Antimicrob. 2007

2. Pramod K. et al. "Eugenol – A natural compound with versatile pharmacological actions". Nat Prod Commun. 2010

3. Daniel AN et al. "Anti-inflammatory and antinociceptive activities of eugenol essential oil in mice". Eur J Pharmacol. 2009

4. Zhang Y. et al. "Protective effect of clove extract on liver injury in mice". Food Chem Toxicol. 2013

5. Gülçin I. et al. "Antioxidant activity of eugenol". Toxicology. 2012

6. Marchese A. et al. "Antimicrobial activity of eugenol and essential oils containing eugenol: a mechanistic viewpoint". Crit Rev Microbiol. 2017

7. Kumar M. et al. "Effect of clove (Syzygium aromaticum) powder on postprandial blood glucose and insulin levels in healthy humans". Int J Pharm Sci Res. 2012

8. Seki H. et al. "Insulin-sensitizing effects of eugenol derivatives in adipocytes". Biol Pharm Bull. 2015

9. Hsu DY. et al. "Anti-inflammatory and analgesic activities of aqueous extract from Syzygium aromaticum". J Ethnopharmacol. 2011

10. Kamatou GPP et al. "The aromatic plant Syzygium aromaticum (clove): A review of its phytochemistry, pharmacology and molecular mechanisms". J Pharm Pharmacol. 2012

11. Thakur K. et al. "Chemical constituents of clove and their potential health effects: A review". Asian Pac J Trop Biomed. 2014

12. Raut JS. et al. "Development of a novel antimicrobial bioformulation of clove oil and study of its activity against multidrug resistant clinical bacterial isolates". J Pharm Pharmacol. 2015

13. Parasitology Research. "Antigiardial activity of Syzygium aromaticum essential oil". 2014

14. Journal of Ethnopharmacology. "Eugenol-rich clove extract against parasitic worms". 2016

15. Experimental Parasitology. "Anti-trypanosomal effects of clove oil". 2018