🛡️ Ergo-Thione+ – Next generation liposomal antioxidant supplement

Ergo-Thione+ is an advanced liposomal dietary supplement developed to support the cells' natural defense against oxidative stress, contribute to healthy aging and maintain general vitality. The product combines four carefully selected antioxidants - L-ergothioneine, glutathione, vitamin C and selenium - delivered in Quicksilver Scientific's patented liposomal technology that provides high bioavailability and rapid absorption via the oral mucosa. The formulation has been developed to work in conjunction with the body's own antioxidant network and support normal physiological processes related to energy turnover, immune function and cellular resilience in a modern and active lifestyle.

Ergothioneine is a sulfur-containing amino acid derivative that occurs naturally in fungi and some plants. The human body has its own specific transport proteins (OCTN1) for ergothioneine, which means that the substance can be taken up efficiently and concentrated in tissues with high metabolic activity and an increased need for protection. Together with glutathione, vitamin C and selenium, Ergo-Thione+ forms a holistic, adaptive and long-term supportive antioxidant complex.

Health benefits
Ergo-Thione+ supports the body's normal functions through ingredients with approved health claims from EFSA:

• Vitamin C helps protect cells against oxidative stress

• Vitamin C contributes to the normal functioning of the immune system

• Vitamin C helps to reduce fatigue and exhaustion

• Vitamin C contributes to normal energy metabolism

• Vitamin C contributes to normal collagen formation for the normal function of skin, blood vessels, cartilage, bones, teeth and gums

• Vitamin C helps to regenerate the reduced form of vitamin E

• Vitamin C contributes to increased absorption of iron

• Selenium helps to protect cells against oxidative stress

• Selenium contributes to the normal functioning of the immune system

• Selenium contributes to normal thyroid function

• Selenium contributes to the maintenance of normal hair and normal nails

• Selenium contributes to normal spermatogenesis

In addition, the combination of the ingredients can support the body's natural detoxification processes, mitochondrial function and general cellular balance through known biochemical mechanisms, without this implying medical claims.

Top 2 main features

• Protection against oxidative stress and support for the immune system
  Ergothioneine, glutathione, vitamin C and selenium work together in the body's antioxidant network and help to neutralize free radicals and protect cell structures.

• Support for cellular energy and natural detox processes
  Glutathione and ergothioneine play central roles in the body's own detoxification and maintenance mechanisms and can support normal mitochondrial function and energy production.

Lesser known but interesting effect
Recent research indicates that ergothioneine can affect cellular signaling pathways linked to stress response and maintenance of cells, including via NRF2-related mechanisms. This has led to the substance being referred to in the research literature as a possible long-term antioxidant nutrient, without this implying medical claims.

Technical details and specifications

• Form: Liposomal liquid liquid

• Volume: 100 ml bottle

• Portions: 20 portions of 5 ml

• Serving size: 5 ml (1 teaspoon)

• Technology: Patented liposomes with particle size approx. 20–100 nm

• Manufacturer: Quicksilver Scientific, Inc., Louisville, Colorado, USA

• Quality: Vegan, completely pure, gluten-free, soy-free, non-GMO, without artificial additives

• Storage: Store in a refrigerator after opening

Grant facts

• Vitamin C (as sodium ascorbate): 600 mg (750% RI)

• Selenium (as methylselenocysteine): 150 µg (273% RI)

• L-ergothioneine: 20 mg

• Glutathione (Opitac™): 200 mg

• Phosphatidylcholine (from purified sunflower lecithin): 260 mg

Ingredients
Water, stabilizer (glycerol), sodium ascorbate, methylselenocysteine, emulsifier (sunflower lecithin), glutathione, ethanol, antioxidant (vitamin E as d-alpha-tocopherol-PEG-1000-succinate), L-ergothioneine, natural flavors (raspberry and hibiscus), sweet orange peel oil (Citrus sinensis L.).

Recommended use
Take 1 teaspoon (5 ml) in mouth and hold for 30-90 seconds before swallowing. Preferably taken on an empty stomach, at least 10 minutes before a meal. Not suitable for children under 18 years of age. Pregnant and breastfeeding women should consult a doctor before use.

Reservation
Allowed to be used by adults. All use of nutritional supplements is at your own risk and should be done in consultation with a doctor. The recommended daily dose should not be exceeded. The effect may vary from person to person. Dietary supplements should not replace a varied diet. Keep out of the reach of children. Uno Vita AS does not claim that the products we market can cure disease.

Disclaimer
Uno Vita is increasingly using artificial intelligence for analyses, summaries and the design of texts. We are not responsible for any errors, inaccuracies or missing information. The information is intended for general information only and is not intended to replace professional medical advice, diagnosis or treatment. Use of products and information is at your own risk.

Freedom of expression and right to information
Uno Vita shares publicly available research and information in line with current laws on freedom of expression, including the UN Universal Declaration of Human Rights Article 19 and the Norwegian Constitution § 100.

Scientific references

1. Halliwell B., Cheah I.K., Tang R.M.Y. Ergothioneine – A stress vitamin with anti-aging, vascular and neuroprotective roles? Biochemical and Biophysical Research Communications, 2018.

2. Cheah IK, Halliwell B. Ergothioneine, recent developments. Redox Biology, 2021.

3. Cheah I.K. et al. Administration of pure ergothioneine to healthy human subjects: Uptake and effects. Antioxidants, 2017.

4. Paul B.D., Snyder S.H. The unusual amino acid L-ergothioneine is a physiological cytoprotectant. Cell Death & Differentiation, 2010.

5. Tang R.M.Y., Halliwell B. Ergothioneine: An under-recognized dietary micronutrient required for healthy ageing? Nutrients, 2021.

6. Ames B.N. Prolonging healthy ageing: Longevity vitamins and proteins. Proceedings of the National Academy of Sciences, 2018.

7. Dubost N.J., Beelman R.B., Royse D.J. Influence of selected mushrooms on antioxidant capacity. Journal of Agricultural and Food Chemistry, 2007.

8. Nakamura T. et al. Transport of ergothioneine by OCTN1. Journal of Biological Chemistry, 2008.

9. Jones DP Redox theory of aging. Redox Biology, 2015.

10. Said H. Oxidative stress: A concept in redox biology and medicine. Redox Biology, 2015.

11. Pizzorno J. Glutathione! Integrative Medicine, 2014.

12. Richie J.P. et al. Randomized controlled trial of glutathione supplementation. European Journal of Nutrition, 2015.

13. Rayman MP Selenium and human health. The Lancet, 2012.

14. Brigelius-Flohé R., Flohé L. Selenium and redox signalling. Archives of Biochemistry and Biophysics, 2017.

15. EFSA Panel on Dietetic Products, Nutrition and Allergies. Dietary Reference Values for vitamin C. EFSA Journal, 2013.

16. EFSA Panel on Dietetic Products, Nutrition and Allergies. Tolerable Upper Intake Level for selenium. EFSA Journal, 2023.

17. Niki E. Role of vitamin C in antioxidant defense. Journal of Nutritional Science and Vitaminology, 2019.

18. Levine M. et al. Vitamin C pharmacokinetics in healthy volunteers. PNAS, 1996.

19. Schauss A.G. Liposomal nutrient delivery systems. Journal of Liposome Research, 2016.

20. Serbinova E. et al. Lipid-soluble antioxidants and cellular protection. Free Radical Biology & Medicine, 1990.

21. Halliwell B. The antioxidant paradox. The Lancet, 2000.