Shitake Betaglukan, 50 ml

Summary
Shitake Betaglukan is a liquid dietary supplement containing Lentinex®, a patented and natural β-(1.3/1.6)-glucan extracted from the Mycelium to Shiitake fungus (Lentinula Edodes) through a proprietary fermentation process. This process preserves the glucan's three-dimensional triple helix structure, which provides high bioactivity and efficiency. The product was developed in Norway with over 20 years of research and has a higher β-glucan concentration than standard Lentinex®. It is free for preservatives, pesticides, solvents and heavy metals. Shitake Betaglukan supports the immune system, protects against oxidative stress and promotes intestinal health. With a daily dose of 1-2 ml, it is a clean, sustainable supplement for those who want to strengthen the body's natural defense.

Health benefits
Shitake Betaglukan contains β- (1.3/1.6) -Glukan, also known as Lentinan, with documented health effects supported by scientific research and in line with approved health claims from the European Food Safety Agency (EFSA). The product supports the body's natural processes without promoting medical claims about the treatment or prevention of diseases. The main benefits include:

• Support to the immune system: β-glucan contributes to the normal function of the immune system by activating immune cells such as macrophages, natural killing cells (NK cells) and T cells, which strengthen the body's defense against pathogens.

• Antioxidant protection: Protects cells from oxidative stress by neutralizing free radicals, which contributes to healthy cell function.

• Intestinal health: Promotes a healthy intestinal flora by supporting the balance of the intestinal microbiota and the normal functions of the digestive system.

• Anti -inflammatory support: Can help maintain normal inflammatory responses, important for general health and well -being.

• Energy and vitality: Can indirectly increase the feeling of energy and well -being by supporting the immune system and protecting cells.

• Cognitive support: Some studies suggest that β-glucan may have an indirect positive effect on cognitive function by supporting general cell health, although this is not an approved health claim.

Important health effects and surprising benefits
The two most documented health effects of shitake beta -glucan are support for the immune system and antioxidant protection. β-glucan activates immune cells such as NK cells and macrophages, which strengthens the body's ability to respond to pathogens. At the same time, it protects the cells from oxidative stress, which is crucial to maintaining healthy cell function over time. A lesser-known advantage is β-glucan's potential role in supporting intestinal health by promoting the growth of beneficial intestinal bacteria, which may have positive effects on digestion and general well-being, especially in the light of research on the intestinal brain axis.

Technical details and subsidy facts
Shitake Betaglukan is produced with a focus on purity, quality and sustainability. Here are the technical specifications:

• Ingredients: Water, glucose, β- (1.3/1.6) -Glukan (0.85–1.15 mg/ml Triple Helix Betaglukan), protein (0.01 %).

• Nutritional content per daily dose (1–2 ml):

  • β-glucan: 0.85–2.3 mg

  • Remaining glucose: <20 mg/ml

  • Total protein: <0.05 mg/ml

• Recommended dosage: 1–2 ml daily, taken directly or mixed in water or food. In the case of active illness, up to 1 ml can be taken every 4 hours, in consultation with a doctor.

• Packaging: 50 ml bottle, enough for 25-50 days of use at standard dosage.

• Look: Light brown liquid, slightly acidic taste, odorless.

• Solubility: Completely soluble in water -based fluids.

• pH: 3–4.

• Specific weight: 0,95–1,05.

• Microbial analysis: Total plate number <100 cfu/g, yeast/fungus <100 cfu/g, absence of pesticides, heavy metals and solvents.

• Storage: Store at 4–35 ° C, should not be frozen. Store dry, closed and inaccessible to children.

• Durability: 24 months in unopened packaging under recommended storage conditions.

• Certifications: Manufactured according to GMP (GOD Manufacturing Practice) and Dshea. Gras-approved and Novel Food Approval.

• Sustainability: Manufactured by sustainable fermentation of shiitake-mycelium, without the use of chemicals or additives.

Reservation
Allowed used for adults. All use of grants takes place at your own responsibility and should be done in consultation with a doctor. Recommended daily dose should not be exceeded. The effect of this product may vary from person to person. Supplements should not replace a varied diet. Not recommended for children under 3 years, pregnant or breastfeeding. Should be kept out of reach of children. Uno Vita AS does not claim that the products we market can cure disease.

Disclaim
Uno Vita is increasingly using artificial intelligence for analyzes, summaries and design of articles. We do not take responsibility for possible errors in texts, articles or descriptions caused by human or computer technology (AI) errors, inaccuracies or lack of information in scientific and medical studies. We encourage all readers to investigate all information critically to ensure that the content is correct. UNO Vita does not claim the medical effects of the products we sell, but we refer to publicly available research in accordance with the right to freedom of speech. The information on this website is only for information purposes and is not intended to replace professional medical advice, diagnosis or treatment. The content should not be used as a basis for diagnoses or selecting treatment forms. All information and material on this website is offered "as it is" without any guarantees, either expressed or implied, including, but not limited to, implicit guarantees of salarability, fitness for a specific purpose or non-violation. Uno Vita disclaims all liability for losses or damage that may occur as a result of the use of information or products from this website. We strongly recommend that you consult a qualified health care provider before starting any new treatment, dietary change or use of supplements. Any use of products or information from this website is done at your own responsibility.

Freedom of speech and right to information
Uno Vita reserves the right to share publicly available research and information on health and wellness technologies, natural substances, vitamins and the like. We do this with reference to national and international laws on freedom of speech, including:

• UN World Declaration of Human Rights (1948): Article 19 ensures the right to freedom of opinion and freedom of speech, including the freedom to receive and disseminate information without regard to boundaries.

• The International Convention on Civil and Political Rights (1966): Article 19 emphasizes the right to freedom of speech and the freedom to apply, receive and notify information and ideas through various media.

• Norwegian Constitution § 100: Ensures freedom of speech, with certain restrictions on the sake of children's protection, privacy, public order and security.

• US First Amendment: Protects freedom of speech against state intervention and provides one of the strongest protections for free expression.

Uno Vita reserves the right to freedom of opinion and freedom of speech in line with these principles.

Scientific references

1. Immunomodulatory effect and biological significance of β-glucans. Pharmaceuticals (Basel). 2023.

2. Stimulatory effect of β-glucans on immune cells. Biomolecules. 2022.

3. Immunomodulatory β-glucan from Lentinus Edodes Activates mitogen-activated protein kinases. Int j mol sci. 2021.

4. Safety and efficacy of a proprietary undenatured beta-glucan on immune function. J clin trials. 2020.

5. Lentinan has a stimulatory effect on inate and adaptive immunity. Anticancer Agents with Chem. 2013.

6. β-glucans: A potential source for Maintaining Gut Health. Front nutr. 2022.

7. Lentinan from Shiitake Selectively Attenuates AIM2 and Non-Canonical Inflammasome Activation. Sci rep. 2019.

8. The Effects of β-Glucan on Human Immune and Cancer Cells. J hematol oncol. 2009.

9. β-glucan extracts from the same edible shiitake mushroom lentinus edodes produc differential in-vitro immunomodulatory and pulmonary cytoprotective effects. Int j mol sci. 2020.

10. β-glucan vaccine adjuvant approach for Cancer Treatment. Int j oncol. 2018.

11. Immunomodulatory Properties of Polysaccharides from Lentinula Edodes. J Fungi (Basel). 2024.

12. Recent Research on the use of beta-glucans in CVD and immune health. Today's Dietitian. 2023.

13. β - 1,3/1.6 -Glucans and Immunity: State of the Art and Future Directions. Mol nutr food res. 2021.

14. β-glucan reduces cortisol plasma levels, enhances inate immune response. Food Chem. 2021.

15. Anti-Tumor Effect of β-Glucan from Lentinus Edodes and the Underlying Mechanism. Sci rep. 2016.

16. CLEC7A AND ITS ROLE IN β-GLUCAN RECOGNITION. Front immunol. 2020.

17. Lentinan: Structure, Bioactivity, and Applications. Wikipedia. 2024.

18. Beta-Glucan: Overview and Health benefits. Wikipedia. 2024.

19. Supplementation with a solar beta-glucan exported from shiitake medicinal mushroom, lentinus edodes mycelium: a crossover, placebo-controlled study in healthy elderly. Nutriters. 2024.

20. Lentinan, β-glucan from Shiitake: A Review on Structure, Conformational Transition, and Gastro-Intestinal Interaction. Food Chem. 2021.

21. Isolation and comparison of α- and β-d-glucans from Shiitake Mushrooms (Lentinula Edodes) with different Biological Activities. Carbohydr polym. 2020.