Nanoemulsified DIM – Advanced support for hormone balance and well-being
Nanoemulsified DIM is an advanced dietary supplement formulated with a phospholipid-based delivery system that makes the absorption of the active ingredient diindolylmethane (DIM) fast and effective. DIM is a bioactive compound that is formed naturally when the body breaks down indole-3-carbinol from cruciferous vegetables such as broccoli, cabbage and Brussels sprouts. The product has been developed for adults who want to support hormone balance, detoxification and general well-being with an easy-to-absorb and modern formulation.

Health effects
• Hormonal balance: DIM supports the breakdown of estrogen into less active metabolites and thus helps to maintain a healthy hormonal balance in both women and men.
• Immune defence: Studies suggest that DIM can positively influence immune functions and contribute to the body's natural defense systems.
• Antioxidant: DIM has shown antioxidant properties that help protect cells against oxidative stress and free radicals.
• Detoxification: Contributes to the body's natural detoxification processes by supporting the breakdown and excretion of foreign substances.
• Anti-inflammatory: DIM can help reduce inflammatory processes in the body through its bioactive properties.
• Skin health: Used by some as support for hormone-related skin problems such as impure skin.
• Weight control: DIM has been studied in connection with hormone balance linked to fat storage and water retention.
• Energy and well-being: Some studies suggest a connection between DIM, energy and subjective mood.

Top health effects and surprising benefit
• Hormonal balance 🌿: DIM can contribute to a healthier estrogen metabolism, and supports the body in reducing the effects of strong estrogen metabolites.
• Immune system 🛡️: DIM has been studied for its possible role in supporting the body's immune response.
• Surprising advantage ✨: DIM can contribute to more effective detoxification by supporting phase I and phase II enzymes in the liver, a function that is often less known among consumers.

Technical details and grant facts
Delivery form: Nanoemulsion for rapid absorption via the oral mucosa.
Serving size: 2 ml (approx. 4 pump pressures).
Content per serving:
• Diindolylmethane (DIM): 20 mg
Other ingredients: Glycerin, water, ethanol, medium chain triglycerides, vitamin E, highly purified phospholipids.

Recommended use: 2–4 pump pressures in the mouth, twice daily. Hold in mouth for 30-90 seconds before swallowing. Use on an empty stomach at least 10 minutes before a meal. Do not use during pregnancy or breastfeeding without consulting a doctor.

Allergens: No known allergens. Free from gluten and GMOs.

Storage: Room temperature, inaccessible to children. Do not use if seal is broken.

Reservation
Allowed to be used by adults. All use of supplements is at your own risk and should be done in consultation with a doctor. The recommended daily dose should not be exceeded. The effect of this product may vary from person to person. Dietary supplements should not replace a varied diet. Should be kept out of the reach of children. Uno Vita AS does not claim that the products we market can cure disease.

Disclaimer
Uno Vita increasingly uses artificial intelligence for analyses, summaries and design of articles. We do not accept responsibility for possible errors in texts, articles or descriptions due to human or computer technology (AI) errors, inaccuracies or missing information in scientific and medical studies. We encourage all readers to examine all information critically to ensure that the content is correct. Uno Vita does not claim medical effects of the products we sell, but we refer to publicly available research in accordance with the right to freedom of expression. The information on this website is for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis or treatment. The content must not be used as a basis for making diagnoses or choosing forms of treatment. All information and material on this website is provided "as is" without any warranties, either expressed or implied. Uno Vita disclaims all responsibility for loss or damage that may arise as a result of the use of information or products from this website. We strongly recommend that you consult a qualified healthcare professional before starting any new treatment, dietary change or use of supplements. Any use of products or information from this website is at your own risk.

Freedom of expression and right to information
Uno Vita reserves the right to share publicly available research and information on health and wellness technologies, natural substances, vitamins and the like, in line with: the UN Universal Declaration of Human Rights (1948) article 19, the International Convention on Civil and Political Rights (1966) article 19, the Norwegian Constitution § 100 and the US First Amendment.

Scientific references

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2. Chen I, McDougal A, Wang F, Safe S. Aryl hydrocarbon receptor-mediated antiestrogenic and antitumorigenic activity of diindolylmethane. Carcinogenesis, 1998.

3. Anderton MJ, Manson MM, Verschoyle RD, et al. Pharmacokinetics and tissue distribution of indole-3-carbinol and its acid condensation products after oral administration to mice. Clin Cancer Res, 2004.

4. Nachshon-Kedmi M, Fares FA, Yannai S. Therapeutic activity of indole-3-carbinol and diindolylmethane in prostate cancer. Nutr Cancer, 2003.

5. Bradlow HL, Sepkovic DW, Telang NT, Osborne MP. Indole-3-carbinol. A novel approach to breast cancer prevention. Ann N Y Acad Sci, 1995.

6. Le HT, Schaldach CM, Firestone GL, Bjeldanes LF. Plant-derived 3,3'-diindolylmethane is a strong androgen antagonist in human prostate cancer cells. J Biol Chem, 2003.

7. Safe S, Papineni S, Chintharlapalli S. Cancer chemotherapy with indole-3-carbinol, bis(3'-indolyl)methane and synthetic analogues. Cancer Lett, 2008.

8. Xue L, Firestone GL, Bjeldanes LF. DIM induces stress responses in human breast cancer cells. J Nutr, 2005.

9. Ahmad A, Sakr WA, Rahman KM. Anticancer properties of indole compounds: mechanism and therapeutic potential. Anticancer Agents Med Chem, 2010.

10. Dalessandri KM, Firestone GL, Fitch MD, et al. Pilot study: Effect of 3,3'-diindolylmethane supplements on urinary hormone metabolites in postmenopausal women. Nutr Cancer, 2004.

11. Chang X, Tou JC, Hong C, et al. DIM protects against oxidative stress in cultured cells. Biochem Biophys Res Commun, 2009.

12. Li Y, Kong D, Bao B, Ahmad A, Sarkar FH. Indole-3-carbinol and DIM in regulation of signal transduction pathways: cancer prevention and therapy. Anticancer Agents Med Chem, 2013.

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15. Sarkar FH, Li Y. Indole-3-carbinol and DIM in prostate cancer chemoprevention. Front Biosci, 2004.

16. McGuire KP, Ngoubilly N, Neavyn M, et al. DIM modulates estrogen metabolism in women at risk for breast cancer. Cancer Epidemiol Biomarkers Prev, 2007.

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18. Thompson LU, Chen JM, Li T, et al. Dietary flaxseed alters estrogen metabolism in postmenopausal women to a greater extent than DIM supplements. Nutr Cancer, 2005.

19. Shertzer HG, Senft AP. Antioxidant properties of DIM in cultured cells. Toxicol Appl Pharmacol, 2000.

20. Martinez-Montemayor MM, Otero-Franqui E, Martinez J, et al. DIM enhances immune function in murine models. Immunopharmacol Immunotoxicol, 2010.

21. Hsu JC, Dev A, Wing A, Bjeldanes LF. DIM as an inhibitor of inflammatory cytokine production. Mol Immunol, 2008.