Pulsed light, biological resonance frequencies and tissue -specific interactions
Integrated subject report based on optical physics, biophysics, photobiology and resonance medicine
Initiation
Pulsed light in the red and near-infrared spectrum (PBM-Photobiomodulation) has for decades been documented to have deep biological effects. When light is pulsed at specific frequencies, it can interact with the body's own electromagnetic resonances-from the full-body level (stroke fluctuations, heartbeat, schumann resonance) to molecular level (DNA vibrations, enzyme activities, water structures). Two main principles are behind: Optical penetration- how wavelength, heart rate frequency, peak effect and heart rate width modulation affect how deep photons reach in biological tissue, and resonant interaction- how light or field modulation at specific frequencies can trigger resonance in biological systems and thus reinforce signal transduction.
Physics behind pulsed light and tissue penetration
Red light in the range of 600–700 Nm is suitable for skin, mucous membranes and surface -sized blood vessels with typical penetration of 1-5 mm. Near-infrared light (700–1100 nm) is absorbed minimally in water and hemoglobin and may penetrate more centimeters into tissues such as muscle, joints and brain. MID-infrared light (1100 nm-20 µm) is stronger in water and mainly provides thermal effects in the surface. The Thz area (0.1-1-10 THZ) has high water absorption, but can also interact with molecular vibrations in DNA and proteins. Pulsation has several functions: High top-effect combined with low average gives less surface heating and deeper penetration, low-frequency pulsion below 100 Hz can entrain'e neurological rhythms and affect bio-rhythms, intermediate frequency from 100 Hz to 10 kHz can modulate reactive oxygen species and promote tissue. While the GHz-Thz area has theoretical relevance of resonances in water and DNA.
Biological resonance frequencies and target structures
Ultralave frequencies below 1 Hz are associated with brain waves, vascular waves and respiratory rhythms, and can affect HRV and blood pressure control. Low frequencies from 1 to 30 Hz covers, among other things, the Schumann resonance of 7.83 Hz associated with cell repair and immunododulation, as well as 10 Hz corresponding to the brain's alfare rhythms and is related to focus, neurora rehabilitation and wound healing. Beta area around 20 Hz can affect nerve cord and Alertness. Intermediate frequencies include 40 Hz gamma waves that have strong evidence of neuroplasticity and amyloid-clearance, while 100 Hz is connected to pain reduction and deeper tissue penetration. High frequencies from 1 kHz to MHz include 8 kHz with documented anti -inflammatory and wound healing effect, as well as piezoelectric effects in collagen around 20-50 kHz. In the GHz-Thz area there are hypothetical couplings to DNA-tension, protein folding and water structures.
Resonance goals in biological systems
Skin and keratinocytes respond to resonances at 7.83 and 10 Hz. Cortical brain areas are sensitive to 10 Hz and 40 Hz. The heart can be affected by rhythms in the range of 0.1–1 Hz and 10 Hz. Mitochondria show response to 10 Hz, 40 Hz and 1 kHz, while collagen structures may have piezoelectric responses at 20-50 kHz. DNA and water show theoretical or weaker evidence of resonances in the Thz area.
Biological frequency areas and effects
Ultralave frequencies (under 1 Hz)
-
0.1 Hz: Resonance with deep brain waves (delta) and vascular waves. Related to deep relaxation and blood pressure control.
-
0.3 Hz: Baroreseptor response. Contributes to stabilization of blood pressure.
-
0.5 Hz: Important for respiration and heart variability (HRV). Strong evidence for optimizing the autonomic nervous system.
Low frequencies (1–30 Hz)
-
1.96 Hz: Vestibular resonance, relevant to the balance organs.
-
2.28 Hz (Nogier A): Associated with cell whiteity and central gray substance.
-
4.56 Hz (nogier B): Effects on metabolism and mood, including antidepressant effect.
-
7.83 Hz (Schumann resonance): Strong evidence for cell repair, stress reduction and immunomodulation.
-
10 Hz: Coincides with the brain's alfarhes. Used to improve focus, stimulate wound healing and support neurorative rehabilitation.
-
20 Hz: Beta waves in the brain. Associated with Alertness, wakefulness and nerve cord.
Intermediate frequencies (30 Hz - 1 khz)
-
40 Hz (gamma frequency): Strong evidence of neuroplasticity, cognitive support and amyloid-clearance in the brain.
-
72.96 Hz (nogier F): Indications of the influence of joints and bones, as well as intellectual stimulation.
-
100 Hz: Well documented for deeper tissue penetration and effective pain reduction.
-
300 Hz: More limited documentation, possible stimulation of stem cell bioenergetics.
-
1 khz: Moderate evidence for support for nerve healing and modulation of oxidative stress.
High Frequencies (1 khz - MHz)
-
8 khz: Strong evidence for wound healing and anti-inflammatory effects.
-
20–50 khz: Indications of piezoelectric effects in collagen and legs. Weak to moderate evidence.
-
100 khz - 1 MHz: Hypotheses of intracellular signaling and membrane resonance. The evidence is currently weak.
GHz-Thz area
-
0.1–3 thz: Theoretical links to hydrogen bonds in water, DNA-tion modia and protein folding.
-
2.4 thz: Suggested resonance in the DNA phosphate skeleton.
-
5–10 thz: Assumed links to lipid membrane dynamics.
The evidence in the GHz-Thz area is weak to moderate, mainly based on laboratory studies and theoretical models.
Luci phi in context
A technology like Luci Phi can supply light between 400 and 1060 Nm with precise control over frequencies from 0.1 Hz to 20 kHz, with the possibility of expansion to MHz. With precision down to 0.1 Hz and in some cases 0.01 Hz it is possible to match biological resonances more accurately. This allows for targeted stimulation of both macro organs, cells, mitochondria and molecular processes.
Conclusion
Pulsed light enables both deeper tissue penetration and targeted bioSonance stimulation. By combining optimum wavelength and accurate frequency control, therapeutic effects can be maximized. The evidence basis varies from strong clinical documentation for certain frequencies and wavelengths to more hypothetical and theoretical models in high -frequency areas. PBM thus appears as an interdisciplinary field that connects physics, biophysics and clinical practice, with the potential for customized treatment based on resonance principles.
Scientific references
-
Hamblin MR, Demidova TN. Mechanisms of Low Level Light Therapy. Proc Spie 6140, 614001 (2006).
-
Chung H et al. The Nuts and Bolts of Low-Level Laser (Light) Therapy. Ann Biomed Eng. 2012; 40 (2): 516–533.
-
Karu ten. Mitochondrial Mechanisms of Photobiomodulation. Photomed Laser Surg. 2010; 28 (2): 159–160.
-
Salehpour f et al. Transcranial Photobiomodulation Therapy for Cognitive Impairment: A Systematic Review. AGEING Res Rev. 2021; 70: 101388.
-
Huang Yy et al. Biphasic dose response in low level light therapy. Dose response. 2009; 7 (4): 358–383.
-
Naeser ma et al. Cognitive Performance After Transcranial Red/Near-Infrared Light Treatments. J Neurotauma. 2014; 31 (11): 1008–1017.
-
AVCI P et al. Low-Level Light Therapy in Skin: Stimulating, Healing, Restoring. Semin cutan with sour. 2013; 32 (1): 41–52.
-
Hashmi Jt et al. Role of Pulsing and Modulation in Photobiomodulation. Lasers Surg with. 2010; 42 (6): 450–466.
-
Wong-Riley Mtt et al. Photobiomodulation benefits primary neurons functionally inactivated by toxins. J Biol Chem. 2005; 280 (6): 4761–4771.
-
Summer Ap et al. Pulsed Laser Light Increase's Photodamage Threshold. J biomed opt. 2005; 10 (2): 024016.
-
Seaweed J et al. Effects of Pulsed 810 Nm Laser on Cell Viability and Nitric Oxide Production. Lasers with sci. 2017; 32 (7): 1589–1596.
-
Schiffer f et al. Psychological benefits After Near Infrared Light Treatment. Psychother Psychosom. 2009; 78 (2): 117–122.
-
Mileva K et al. Pulsed Low-Level Laser Therapy on Peripheral Nerve Regeneration. Lasers with sci. 2014; 29 (1): 59–66.
-
UEDA Y et al. Pulsed Near-Infrared irradiation therapy for Chronic Pain. Laser ther. 2011; 20 (2): 87–93.
-
Yaroslavsky an al. Optical Properties of Human Skin and Mucous Tissues 400–2000 Nm. J biomed opt. 2002; 7 (3): 305–310.
-
Enwemeka CS et al. Low-power lasers in tissue repair and pain control: meta-analysis. Photomed Laser Surg. 2004; 22 (4): 323–329.
-
POPP FA. About the coherence of biophotons. Macroscopic Quantum Coherence. World Scientific. 1998.
-
Fröhlich H. Long-Range Coherence and Energy Storage in Biological Systems. INT J Quantum Chem. 1968; 2 (5): 641–649.
-
Bókkon in et al. Phospene Phenomenon: A New Concept. With hypotheses. 2010; 75 (6): 531–540.
-
Cosic I. Macromolecular Bioactivity: Resonant Interaction Between Macromolecules? IEEE TRAND BIOMED ENG. 1994; 41 (12): 1101–1114.
-
Kurian p et al. Fröhlich condensates from Myelin Sheath Biophotons. Sci rep. 2016; 6: 36508.
-
Pokorný J. Physical Aspects of Biological Activity and Cancer. AIP CONF PROC. 2012; 1479 (1): 178–191.
