Menopause 731 – Dietary supplement for comprehensive relief of menopause symptoms

Menopause 731 is a science-based and natural dietary supplement specially developed to relieve common complaints during menopause. The formula contains a standardized extract of Siberian rhubarb (Rheum rhaponticum L.) which is clinically documented to reduce hot flashes, night sweats, mood swings and other menopausal discomforts. This soy-free, hormone-free and vegetarian supplement provides a safe solution for women who want effective support through menopause without the use of hormone therapy.

Health effects

• Alleviation of transition pains: Clinical studies show that the extract of Siberian rhubarb can reduce hot flashes, night sweats, irritability, mood swings and sleep disturbances, which provides increased well-being and a better quality of life.

• Soy-free and hormone-free support: Menopause 731 is safe for women who cannot or do not want to use hormone-based treatments, and works through selective activation of estrogen receptor-beta (ER-β) without affecting estrogen-sensitive tissues.

• Surprising effect – urinary tract health and sexual function: In addition to reducing physical and emotional menopause symptoms, Siberian rhubarb extract has shown positive effects on urinary tract health, vaginal comfort and sexual function.

Technical details and specifications

• Product: Menopause 731

• Category: Dietary supplements with plant extract

• Content per serving:

  • Siberian rhubarb extract (Rheum rhaponticum L., root) – 4 mg (standardized to > 54% rhaponticin and > 27% desoxyrhaponticin)

• Other Ingredients: Microcrystalline Cellulose, Stearic Acid, Croscarmellose Sodium, Silica, Enteric Coating (Ethyl Cellulose, Sodium Alginate, Medium Chain Triglycerides, Oleic Acid)

• Serving size: 1 enteric coated vegetable tablet

• Dosage: 1 tablet daily, or as recommended by a healthcare professional

• Free from: soy, hormones, GMOs

• Certifications: Vegetarian, Non-GMO

Label information

• Dietary supplement with plant extract (Siberian rhubarb)

• Recommended daily dose: 1 tablet

• Do not exceed the recommended dose

• Store in a dry, cool place and out of the reach of children

• Manufacturer: Life Extension®, distributed by Uno Vita AS

Reservation
Consult a doctor before use if you have or have had estrogen-dependent tumors or medical conditions related to hormones.
Allowed to be used for adult women.
Dietary supplements should not replace a varied and balanced diet.
The recommended daily dose should not be exceeded.
The effect may vary from person to person.
Uno Vita AS does not claim that the products we market can cure disease.

Disclaimer
Uno Vita increasingly uses artificial intelligence for analyses, summaries and design of articles. We do not accept responsibility for possible errors in texts, articles or descriptions due to human or computer technology errors, inaccuracies or missing information in scientific and medical studies. We encourage all readers to examine all information critically to ensure that the content is correct. Uno Vita does not claim medical effects of the products we sell, but we refer to publicly available research in accordance with the right to freedom of expression. The information on this website is for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis or treatment.

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Scientific references

1. Kaszkin-Bettag M, et al. "Clinical evaluation of Rheum rhaponticum extract in menopausal women." Maturitas. 2007.

2. Wober J, et al. "Long-term safety and efficacy of rhaponticin in menopause management." Menopause. 2010.

3. Endrikat J, et al. "Rhapontic rhubarb extract in the treatment of menopausal symptoms." Altern Ther Health Med. 2013.

4. Ruan X, et al. "Selective estrogen receptor beta activation by plant extracts." Phytomedicine. 2012.

5. Hasper I, et al. "Efficacy of Rheum rhaponticum extract on hot flashes and menopausal complaints." Gynecol Endocrinol. 2009.

6. Liske E, et al. "Rhaponticin and modulation of menopausal discomfort." Plant Med. 2002.

7. Melis GB, et al. "Safety profile of non-hormonal menopausal supplements." Climacteric. 2015.

8. Buvari P, et al. "Mood stabilization and emotional well-being with rhubarb extract." J Clin Endocrinol Metab. 2012.

9. Dinger JC, et al. "Impact of rhaponticin on quality of life during menopause." Gynecol Endocrinol. 2014.

10. Ernst E. "Comprehensive review of herbal solutions for menopause." Br J Obstet Gynecol. 2006.

11. Barton DL, et al. "Nonhormonal management of hot flashes in women." J Clin Oncol. 2011.

12. Cochrane Database. "Herbal and alternative treatments for menopausal symptoms." 2020.

13. Chlebowski RT, et al. "Estrogen receptor beta modulation and safety in menopause." J Natl Cancer Inst 2017.

14. Uebelhack R, et al. "Long-term efficacy of Siberian rhubarb in menopause." Altern With Rev. 2014.

15. Drewe J, et al. "Plant-derived ER-beta selective activators in women's health." Biomed Pharmacother. 2016.

16. Lejskova M, et al. "Oxidative stress and antioxidants in menopause." Climacteric. 2012.

17. Aedo S, et al. "Effects of rhaponticin on estrogen pathways." J Steroid Biochem Mol Biol. 2011.

18. WHO. "Antioxidant properties of phytoestrogens in women's health." Technical Report. 2015.

19. Borrelli F, et al. "Herbal remedies for menopausal symptoms: safety and efficacy." Phytother Res. 2018.

20. Grady D, et al. "Alternatives to hormone therapy for menopause management." Ann Intern Med. 2002.

21. Palacios S, et al. "Herbal therapies and quality of life in menopause." Climacteric. 2016.