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Food Sensitivity Relief with Diamine Oxidase (DAO)

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Food Sensitivity Relief with Diamine Oxidase (DAO) has been reordered and will be shipped as soon as it is back in stock.

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Food Sensitivity Relief with Diamine Oxidase (DAO) is a plant-based dietary supplement developed to support the breakdown of histamine in the gut from histamine-rich food. Each capsule contains DAO activity of 20,000 HDU from pea sprouts, and the product is GMO-free, gluten-free and without animal ingredients. This makes it relevant for adults who want digestive support at meals that are often associated with bloating, gas or other histamine-related discomfort.

Many people experience digestive problems after meals, especially with foods such as cured meats, aged cheeses, fermented foods and wine. Diamine oxidase is an enzyme that helps break down histamine in the digestive system. Compared to traditional DAO products from animal sources, this formula uses DAO from pea sprouts, providing a plant-based alternative for those seeking plant-based supplements for stomach and intestinal health.

  • 20,000 HDU DAO per capsule from dehydrated pea sprout powder
  • Supports histamine breakdown in the gut with histamine-rich food
  • Can contribute to reduced bloating, gas and digestive discomfort in sensitive people
  • Plant-based, vegetarian, GMO-free and gluten-free
  • Practical use before heavier meals, up to three times a day

The product is particularly suitable in situations where the histamine content in the food is often higher than usual, for example at restaurant meals, parties, tapas, cured meats, mature cheeses or a glass of wine with the meal. In such contexts, many people want targeted digestive comfort without changing the entire meal. Unlike general digestive enzymes, this formula specifically targets histamine metabolism in the gut.

Content per capsule is 4.3 mg of dehydrated pea sprout powder with a DAO activity of 20,000 HDU. Other ingredients are microcrystalline cellulose, vegetable cellulose in the capsule, silica and vegetable stearate. The product is manufactured in the USA to high standards for purity and quality. This type of specification makes the product easier to evaluate for people looking for measurable information and clearly declared content.

Directions for use are one capsule before heavier meals, up to three times a day, or as recommended by healthcare professionals. The product has been developed to support the breakdown of histamine, but is not intended to prevent severe allergic reactions or gluten-related reactions. For adults who want a more precise dietary supplement for digestion in case of histamine sensitivity, this may be a more targeted choice than broad-spectrum digestive supplements.

Referenced research on DAO and histamine intolerance describes the connection between reduced histamine breakdown and digestive problems in some people. Published sources include, among others, works by Maintz, Novak, Reese and Izquierdo-Casas on histamine intolerance, DAO activity and dietary management. This is not documentation of a medical effect for everyone, but provides professional context for why DAO is used as nutritional support for histamine-related discomfort.

Allowed to be used by adults. All use of supplements is at your own risk and should be done in consultation with a doctor. The recommended daily dose should not be exceeded. The effect of this product may vary from person to person. Dietary supplements should not replace a varied diet. Should be kept out of the reach of children. Uno Vita AS does not claim that the products we market can cure disease.

Uno Vita increasingly uses artificial intelligence for analyses, summaries and design of articles. We do not accept responsibility for possible errors in texts, articles or descriptions due to human or computer technology (AI) errors, inaccuracies or missing information in scientific and medical studies. We encourage all readers to examine all information critically to ensure that the content is correct. Uno Vita does not claim medical effects of the products we sell, but we refer to publicly available research in accordance with the right to freedom of expression. The information on this website is for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis or treatment. The content must not be used as a basis for making diagnoses or choosing forms of treatment. All information and materials on this website are provided "as is" without any warranties, either expressed or implied, including, but not limited to, implied warranties of merchantability, fitness for a particular purpose or non-infringement. Uno Vita disclaims all responsibility for loss or damage that may arise as a result of the use of information or products from this website. We strongly recommend that you consult a qualified healthcare professional before starting any new treatment, dietary change or use of supplements. Any use of products or information from this website is at your own risk.

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References Schnedl W, Ferber K, Lackner S, et al. Enzymatic characteristics of diamine oxidase from pea (Pisum sativum L.). J Enzyme Inhib Med Chem. 2014;29(6):1-9. Reese I, Ballmer-Weber BK, Worm M. Histamine intolerance: the current state of diagnostic and therapeutic knowledge. Allergol Select. 2017;1:6-14. Sattler J, Häfner D, Klotter HJ, et al. Food-induced histaminosis as an epidemiological problem: plasma histamine elevation and altered histamine metabolizing capacity in healthy females after oral histamine administration. Scand J Gastroenterol. 1988;23(11):1221-8. Maintz L, Novak N. Histamine and histamine intolerance. Am J Clin Nutr. 2007;85(5):1185-96. Lomer MC, Parkes GC, Sanderson JD. Review article: lactose intolerance in clinical practice – myths and realities. Aliment Pharmacol Ther. 2008;27(2):93-103. Schink M, Konturek P, Tietz E, et al. Microbial patterns in patients with histamine intolerance. J Physiol Pharmacol. 2018;69(4):579-93. Wantke F, Gotz M, Jarisch R. Histamine-free diet: treatment of choice for histamine intolerance. Clin Exp Allergy. 1993;23(10):982-5. Manzotti G, Breda D, Di Gioacchino M, Burastero SE. Serum diamine oxidase activity in patients with histamine intolerance. Int J Immunopathol Pharmacol. 2016;29(1):105-11. Maintz L, Bieber T, Novak N. The relevance of diamine oxidase (DAO) for the integrity of intestinal function in health and disease. J Clin Immunol. 2008;28(5):496-504. Izquierdo-Casas J, Comas-Basté O, Latorre-Moratalla M, et al. Histamine intolerance and dietary management: a comprehensive review. Nutrients. 2019;11(9):1-15. Aguilera J, Benítez I, Gálvez A. Mechanisms of food allergy. Allergy. 2006;61(1):60-9. Kovacova-Hanuskova E, Buday T, Gavliakova S, et al. Histamine, histamine intoxication and intolerance. Allergol Immunopathol (Madr). 2015;43(5):498-506.