TMG 500 mg is a dietary supplement with trimethylglycine, also known as betaine anhydrate, developed for adults who want support for normal homocysteine metabolism. Each capsule provides 500 mg of TMG, and the recommended daily dose of 2 capsules provides a total of 1000 mg. The product is tasteless, non-GMO, suitable for vegetarians and formulated with few ingredients. EFSA has approved the health claim that betaine contributes to normal homocysteine ​​metabolism, provided that the product contains at least 500 mg per portion and that the consumer is informed that a beneficial effect is achieved with a daily intake of 1.5 g of betaine.

Trimethylglycine acts as a methyl donor in the one-carbon metabolism and supports the conversion of homocysteine ​​to methionine. This makes TMG relevant in the context of cardiovascular health, methylation and general metabolic balance. Compared to supplements that only add B vitamins, TMG provides an alternative methyl pathway that can be particularly relevant when you want broad support for homocysteine ​​balance. It can also be combined with vitamin B6, folate and vitamin B12 to support the same biochemical axis.

• 500 mg trimethylglycine per capsule and 1000 mg per recommended daily dose
• Betaine contributes to normal homocysteine metabolism in line with EFSA regulation 432/2012
• Vegetable capsules without known allergens, suitable for vegetarians and non-GMO
• Supports methylation and the methionine cycle as part of one-carbon metabolism
• Practical for daily use in the morning, with a neutral and tasteless formulation

In nutritional research, betaine is also mentioned in connection with the liver's phospholipid metabolism, fat transport and cellular energy biochemistry. This is informative mechanistic background and not a medical claim. Clinical and experimental literature also describes connections between betaine and markers related to inflammation balance, including NF-kB and TNF-alpha. For individuals following a targeted regimen in biohacking, metabolic health, or cardiovascular support, this may be a relevant addition to a broader strategy.

The use is simple: adults take 2 capsules in the morning with water, preferably on an empty stomach, or as advised by a healthcare professional. In practice, the product can be suitable for people who want to monitor homocysteine ​​levels, who use B6, folate or B12, or who want a pure supplement without unnecessary additives. Compared to powder forms, capsules are easier to dose precisely and easier to use when traveling or in a busy everyday life.

The ingredients are trimethylglycine, vegetable cellulose, glycerin and purified water. The product contains no vitamins or minerals with a reference intake, and therefore no RI percentage is given. In order to base the EFSA claim on homocysteine ​​metabolism, the consumer must be aware that the beneficial effect is achieved with 1.5 g of betaine daily. This product provides 1.0 g at the recommended daily dose, and dosages beyond this should be considered in consultation with healthcare personnel. EFSA has also pointed out that consumption of 4 g per day over at least six weeks can increase total cholesterol, so higher doses are not recommended without follow-up.

TMG 500 mg is suitable for adults who want a documentable, simple and regulatory-compliant betaine supplement for daily use. Keep out of the reach of children. Pregnant, breastfeeding and people under medical treatment should consult a doctor before use. Read more if you want a practical supplement for homocysteine ​​balance, methylation and general metabolic support.