Resveratrol – for everyone over 40 years old
Resveratrol has a wide range of effects, is harmless, provides anti-aging effects, and may counteract a number of health problems
Comprehensive health-promoting effects
Resveratrol has been reported to be able to improve the therapeutic outcome in patients suffering from diabetes mellitus, obesity, colorectal cancer, breast cancer, myeloma, metabolic syndrome, hypertension, Alzheimer's disease, stroke, cardiovascular diseases, kidney diseases, inflammatory diseases, and rhinopharyngitis (an inflammation of the nasal and pharyngeal mucosa).
What is Resveratrol?
Resveratrol is a plant compound found in various plants, especially red grapes, some berries, and Japanese knotweed. Most of resveratrol’s benefits have traditionally been attributed to its powerful antioxidant and anti-inflammatory effects. New research now shows that resveratrol also stimulates cells to behave as if they had been exposed to calorie restriction, the most powerful life-extending activity we know of. Through its action on potent cellular regulatory proteins called sirtuins, resveratrol mimics calorie restriction (such as fasting, intermittent fasting, a ketogenic diet, a low-carb diet, etc.), stimulates healthy cells to survive, and sick cells to die in an organized manner.Resveratrol-stimulated sirtuin activation (sirtuins are proteins that function as signaling molecules) is believed to be responsible for many of the health benefits associated with resveratrol supplementation, including protection against age-associated disorders such as cardiovascular disease, metabolic syndrome, neurodegenerative disorders, and cancer.
Resveratrol provides a broad range of health-promoting effects, which may help improve insulin sensitivity (counteracting diabetes and obesity), activate anti-aging genes, and reduce chronic inflammation. The effects of resveratrol influence virtually all organ systems of the body. Among the potential benefits observed in a wide range of studies, resveratrol has also been shown to:
Anti-aging by promoting longevity
Resveratrol intake is associated with longer lifespan in a range of organisms, animals, and humans.
Improves metabolism (metabolic health)
Metabolism is essential for all systems in the body. Resveratrol contributes to healthy metabolism. Clinical research shows that the substance may help improve insulin sensitivity and normalize lipid levels, assist with diabetes control, reduce body weight, and improve gut flora. The effects of resveratrol also «mimic» beneficial effects achieved through a ketogenic diet and exercise, both of which improve metabolism.
Protects the heart
In clinical and preclinical studies, resveratrol has been shown to improve blood vessel function and blood pressure. Resveratrol may help counteract underlying causes of cardiovascular disease
Protects the brain
Data from clinical studies have shown that resveratrol may reduce neuroinflammation and the accumulation of abnormal proteins associated with neurodegenerative diseases such as Alzheimer's and Parkinson's disease.
Immune-supporting and anti-inflammatory effects
Resveratrol has demonstrated immunomodulatory effects in preclinical studies, which may strengthen healthy immune function to defend against various disease-causing organisms and toxins. It also has anti-inflammatory properties.
May help counter cancer
Studies show that resveratrol has anti-cancer activity, may block abnormal cell growth, may kill unhealthy cells, and may counter the spread of these cells in the body. Part of the effect is attributed to activation of Nrf2 signaling, which affects gene expression and how the cell handles oxidative stress
Bioavailability is crucial for good effect
The term bioavailability refers to how well a substance is absorbed in the intestine and taken up by the body's cells. With increased bioavailability, hydrogel resveratrol may help ensure that all the health benefits of Resveratrol can be fully realized. One challenge with resveratrol has been finding ways to make it more bioavailable. Despite good initial absorption, resveratrol is rapidly metabolized, leaving little of the original compound circulating in the blood. Through the development of its hydrogel fiber blend, Life Extension's research team has made it possible for their Reservatrol Elite products to provide up to 10 times higher bioavailability compared with regular resveratrol supplements. This improves the amount of time and the level at which resveratrol can deliver its many benefits throughout the body.
Summary
We have long known that resveratrol has strong antioxidant and anti-inflammatory effects, making it a generally important and recommended dietary supplement that may help prevent age-related chronic disease. By activating sirtuins, resveratrol stabilizes DNA, which counteracts cancer-related changes, switches on antioxidant and anti-inflammatory defense mechanisms, and even instructs certain cells to undergo organized cell death through apoptosis (only diseased cells). The end result is an almost incredible range of health benefits, from reducing cardiovascular risk factors to protection against neurodegenerative disease to cancer prevention. In fact, resveratrol is now being actively explored by major pharmaceutical companies eager to profit from its power by creating new substances derived from the natural molecule
You do not need to wait for the natural molecule Resveratrol to become available as a synthetically produced medicine at the pharmacy. You can start taking a supplement with good bioavailability today and begin experiencing the beneficial effects immediately.
Research links:
Research on Resveratrol from Google Scholar, click here!
Research on Resveratrol from PubMed, click here
