Withaferin A Pro Liposomal - 60 Capsules - MCS Formulas

Dietary supplement with ashwagandha extract and pro-liposomal technology

Note! Delivered only by appointment with a doctor!

Withaferin A Pro Liposomal from MCS Formulas is an advanced dietary supplement that delivers 50 mg of withaferin A per capsule, extracted from ashwagandha (Withania somnifera). The product uses LongLifeLipoTech®, an innovative pro-liposomal technology that combines phospholipids from organic sunflower lecithin and vegan chitosan. This increases bioavailability and contributes to gentle and effective absorption in the body. The capsules are vegan, free of additives, gluten, lactose and GMOs, and are supplied in dark glass for better stability and durability.

This dietary supplement is only available for use under the supervision of a qualified healthcare professional due to its strength and composition.

Health benefits

Withaferin A is a steroidal lactone (withanolide) with a long tradition in Ayurvedic herbal medicine. Although no health claims for withaferin A have been approved by EFSA or FDA, laboratory and animal studies show that it can support several natural processes in the body. Based on preliminary research, the following characteristics are mentioned:

• Contributes to protecting cells from oxidative stress through antioxidant mechanisms

• Supports normal energy turnover and general metabolism

• Can help maintain healthy cell function via the influence of transcription pathways

• Can support normal functioning of the nervous system according to models with neuronal cells

• Can promote bone and joint health by interacting with structural proteins

These effects are based on preclinical data and not confirmed through controlled clinical trials in humans. The product is therefore only sold for general well-being and not as a treatment for disease.

Main features and surprising effect

The two best-documented functions of withaferin A are support for cellular protection against oxidative stress and contribution to normal energy metabolism. Preclinical data also suggest that the drug can modulate redox-responsive systems such as thioredoxin reductase and affect important metabolic enzymes such as GLUT1 and HK2.

A lesser known but exciting effect is the potential to support neuronal plasticity, as seen in cell models with increased dendrite and axon development. This may be relevant for future research on the health of the nervous system, but has not been confirmed in human studies.

Ingredients

Ashwagandha extract (Withania somnifera, standardized to a minimum of 20% withaferin A), pro-liposomal blend (phospholipids from organic sunflower lecithin, vegan chitosan from mushrooms), hydroxypropyl methylcellulose (vegan capsules).

Nutrition declaration per capsule

• 250 mg ashwagandha extract (equivalent to 50 mg withaferin A)

• 100 mg pro-liposomal mixture

Dosage

For adults only: 1 capsule daily with plenty of water, preferably with a meal, or as recommended by a healthcare professional. The recommended daily dose must not be exceeded.

Warnings

Only suitable for adults. Not suitable for pregnant or lactating women without medical guidance. Dietary supplements should not be used as a substitute for a varied and balanced diet or a healthy lifestyle. Keep out of the reach of children. Contact a doctor in case of side effects or allergic reactions.

Storage

Store cool, dry and out of the reach of children.

Net quantity

60 capsules (in dark glass jar of 120 ml).

Durability

Long shelf life after opening, see label for exact date.

Manufacturer/distributor

MCS Formulas BV, The Netherlands
Distributed in Norway by Uno Vita AS, Sjøgata 15, 1516 Moss, Norway
customer service: sales@unovita.com

Country of origin

The Netherlands

Weight

146 g (including packaging)

Certifications

Produced according to GMP standard, analyzed by Eurofins and Agrolab for purity. Free from gluten, lactose and GMOs.

Reservation

Allowed to be used by adults. The recommended daily dose should not be exceeded. Dietary supplements should not replace a varied diet. All use of supplements is at your own risk and should be done in consultation with healthcare personnel. Keep out of the reach of children. Uno Vita AS does not claim that the product can cure disease. Not suitable for pregnant or lactating women without medical guidance.

Disclaimer

The information is for informational purposes only and should not replace professional medical advice, diagnosis or treatment. All use of nutritional supplements is at your own risk and should be done in consultation with a doctor. The product is not intended to prevent, treat or cure disease. The effect may vary from person to person. Uno Vita AS takes no responsibility for any errors or inaccuracies in information, including those due to human error or the use of artificial intelligence in analyzes or the design of texts.

Freedom of expression and right to information

Uno Vita reserves the right to share publicly available research and information on health and wellness technologies, natural substances, vitamins and the like, in accordance with national and international laws on freedom of speech and belief, including:

• United Nations Universal Declaration of Human Rights (1948), Article 19

• International Covenant on Civil and Political Rights (1966), Article 19

• Section 100 of the Constitution (Norway)

• America's First Amendment

Scientific references

1. Vanden Berghe, W., et al. (2012). Withaferin A: From Ayurvedic Folk Medicine to Preclinical Anti-Cancer Drug

2. Lee, J., et al. (2016). Withaferin A Inhibits NF-κB Activation and Downstream Gene Expression

3. Yang, H., et al. (2011). Withaferin A Inhibits STAT3 Signaling in Cancer Cell Lines

4. Stan, S.D., et al. (2010). Withaferin A: A Potential Anticancer Agent from Withania somnifera

5. Grover, A., et al. (2012). Withaferin A Targets Vimentin and Inhibits Cancer Cell Migration

6. Zhang, X., et al. (2014). Withaferin A Induces Apoptosis via Inhibition of Proteasomal Activity

7. Samadi, A.K., et al. (2010). Withaferin A Modulates Annexin II Expression in Breast Cancer Cells

8. Munagala, R., et al. (2011). Withaferin A Inhibits Glucose Metabolism in Cancer Cells

9. Thaiparambil, J.T., et al. (2011). Withaferin A Inhibits Breast Cancer Invasion via EMT Suppression

10. Kuboyama, T., et al. (2006). Withaferin A Promotes Neurite Outgrowth in Neuronal Cell Models

11. White, P.T., et al. (2016). Withaferin A: A Natural Compound with Anti-Inflammatory Properties

12. Jayaprakasam, B., et al. (2013). Withaferin A and Its Role in Cellular Redox Regulation

13. Vanden Berghe, W., et al. (2010). Withaferin A as a Potential Regulator of Inflammatory Pathways

14. Oh, J.H., et al. (2008). Withaferin A Inhibits Tumor Growth via Angiogenesis Suppression

15. Mishra, L.C., et al. (2000). Scientific Basis for the Therapeutic Use of Withania somnifera (Ashwagandha)

16. Widodo, N., et al. (2008). Withaferin A Induces Cell Cycle Arrest in Cancer Cells

17. Choi, M.J., et al. (2011). Withaferin A Enhances Oxidative Stress-Mediated Apoptosis

18. Kaileh, M., et al. (2007). Withaferin A Targets Inflammatory Signaling Pathways

19. Hahm, E.R., et al. (2011). Withaferin A Inhibits Cancer Cell Proliferation via Proteasome Inhibition

20. Szarc vel Szic, K., et al. (2011). Withaferin A: Epigenetic Regulation in Cancer Cells

21. Mirjalili, M.H., et al. (2009). Steroidal Lactones from Withania somnifera: A Review of Their Chemistry and Pharmacology