Glucan 300 (60 capsules) – highly purified beta-1,3-D-glucan for daily immune balance

Summary
Glucan 300 is a dietary supplement based on highly pure beta-1,3-D-glucan extracted from the cell wall of Saccharomyces cerevisiae. The product has been developed with a focus on high purity, documented quality and consistent content, and is used by people who want to support the body's normal immune function as part of a long-term diet and a healthy lifestyle. Glucan 300 is free of gluten, purines, live yeast and declarable allergens, and is suitable for vegetarian use.

Health benefits
• 🧬 beta-glucans have been investigated in scientific literature for their role in the body's normal immune-related processes
• 🛡️ can help support the normal function of the immune system as part of a varied diet
• ⚖️ is associated with immune balance without being stimulating in the classical sense
• 🌿 suitable for daily and long-term use in adults
• 🔁 often used during periods of increased load, seasonal variations or changes in lifestyle

Beta-1,3-D-glucans are complex polysaccharides that form part of research into the interaction between dietary factors and the immune system's normal response mechanisms.

Technical details / specifications
• Raw material: beta-1,3-D-glucan from Saccharomyces cerevisiae
• Standardized to a minimum of 85% beta-1,3-D-glucan complex (tested with GEM analysis)
• Without live yeast, gluten, purines, GMOs and artificial additives
• Vegetable capsules
• Manufactured under strict quality controls
• Each batch is tested for purity and content

Label information
Statutory designation: dietary supplement

Ingredients per capsule:
• Beta-1,3-D-glucan (from Saccharomyces cerevisiae) – 300 mg
• Capsule: vegetable capsule (hypromellose, water)

Recommended daily dose:
1 capsule daily, taken on an empty stomach with water, or as recommended by healthcare professionals.

Reference intake (RI): not established.

Allergens: no declarable allergens added.

Storage: dry and cool, tightly closed and inaccessible to children. Do not use if the seal is broken.

Manufacturer: manufactured under quality control according to current standards
Importer/responsible business in the EEA: Uno Vita AS, Moss, Norway
Batch/Lot and best before: stated on the packaging

Reservation
Allowed to be used by adults. The recommended daily dose should not be exceeded. The effect may vary from person to person. Food supplements should not be used as a substitute for a varied and balanced diet and a healthy lifestyle. People who are pregnant, breastfeeding, have autoimmune conditions or are under medical follow-up should consult a doctor before use.

Disclaimer
This product is a dietary supplement and is not intended to diagnose, treat, cure or prevent disease. The information is provided as general consumer information.

Freedom of expression
The information is based on publicly available research and specialist literature, and is shared in line with freedom of expression, Section 100 of the Constitution, Article 19 of the UN Universal Declaration of Human Rights and applicable Norwegian and European regulations.

Scientific references

1. Vetvicka V, Vetvickova J. β-Glucan effects on immune reactions. Open Biochem J, 2012.

2. Vetvicka V, Vetvickova J. 1,3-Glucan: Silver Bullet or Hot Air? Open Glycoscience, 2010.

3. Volman JJ et al. Dietary modulation of immune function by β-glucans. Crit Rev Food Sci Nutr, 2008.

4. Brown GD, Gordon S. Immune recognition of fungal β-glucans. Cell Microbiol, 2005.

5. Hong F et al. Mechanisms of orally administered β-glucans. J Immunol, 2004.

6. Cramer DE et al. β-Glucan and hematopoietic recovery. Blood, 2006.

7. Tzianabo's AO. Polysaccharide immunomodulators. Clin Microbiol Rev, 2000.

8. Chan GC et al. Polysaccharides from medicinal fungi. Appl Microbiol Biotechnol, 2009.

9. Wasser SP. Medicinal mushrooms and polysaccharides. Appl Microbiol Biotechnol, 2002.

10. Ooi VE, Liu F. Immunomodulation by fungal polysaccharides. J Ethnopharmacol, 2000.

11. Rieder A et al. β-Glucans in human nutrition. Nutrients, 2017.

12. Akramiene D et al. Effects of β-glucans on the immune system. Medicine, 2007.

13. Murphy EA et al. β-Glucan supplementation and immune function. J Appl Physiol, 2008.

14. Goodridge HS et al. Dectin-1 signaling and β-glucans. Nat Rev Immunol, 2009.

15. Novak M, Vetvicka V. Glucans as biological response modifiers. Endocr Metab Immune Disorder Drug Targets, 2009.

16. Kim HS et al. Yeast-derived β-glucans. Int J Mol Sci, 2011.

17. Vetvicka V. β-Glucans in health and disease. Int J Med Mushrooms, 2019.

18. Stier H et al. Immune-modulating effects of β-glucans. Journal of Nutrition, 2014.

19. McFarlin BK et al. β-Glucan and immune health. J Sports Sci Med, 2005.

20. EFSA Panel on Dietetic Products. Scientific opinion on β-glucans. EFSA Journal.

21. Ikegami S et al. Safety evaluation of yeast-derived polysaccharides. Food Sci Nutr, 2018