Dopamine Advantage (30 vegetarian capsules) 
Mental sharpness & motivation

Dopamine is a “feel good” neurotransmitter also essential for cognitive function. Our phellodendron bark powder and Adenosylcobalamin B12 formula helps your brain maintain normal dopamine levels.

What Is Dopamine Advantage?
Our innovative formula supports motivation and focus, thanks to a combination of phellodendron bark powder and a special neurologically active form of vitamin B12. Together, these nutrients protect your brain cells from cellular stress and encourage healthy dopamine levels, promoting concentration and helping you stay focused on your task at hand.

Dopamine is key to feeling good and motivated. Dopamine Advantage helps ensure your brain has enough to go around.
Dopamine Advantage Benefits
Helps maintain youthful dopamine levels
Helps stay sharp & motivated
Promotes healthy cognitive function
Normal Dopamine Levels, Less MAO-B Activity
Phellodendron bark (amur cork tree) is known for its neuroprotective properties; it protects the delicate cells that make up your brain and nervous system from cellular stress. Research shows phellodendron bark effectively inhibits the enzyme monoamine oxidase B (MAO-B for short) that breaks down dopamine. By inhibiting this enzyme, your brain has more dopamine to work with, helping you feel more focused and motivated.

Life Extension - Why Do We Do It?
The Best Supplements Science Can Offer
When putting something in your body, you should be confident that you’re getting the nutritional benefits your body deserves. We've been delivering the highest-quality products—backed by science and formulated with the finest ingredients—for over 40 years.

What Matters to You, Matters to Us
We're committed to empowering you to live a healthier life. Whether it’s finding sustainable partners for our ingredients or funding the latest anti-aging research, we're all about your health & wellness.

Highly Recommended
98% of our customers recommend us to family and friends. We're very proud of that because our loved ones matter to us—and we're willing to bet you feel the same way.

Product Transparency
40 years of research dedicated to bringing you premium, scientifically-validated formulations.

Product Details
Dopamine Advantage is our latest brain health formula. It is designed to support motivation and focus by combining phellodendron bark powder with a special neurologically active form of vitamin B12. Together, these nutrients protect your brain cells from cellular stress and encourage healthy dopamine levels, promoting healthy mood, concentration and helping you stay focused on your task at hand.

Maintaining healthy dopamine levels
Dopamine is a neurotransmitter or brain chemical that’s produced in your brain and released into synaptic clefts, the microscopic spaces between your neurons, to relay signaling information from one neuron to the next. Unfortunately, factors such as nutrition, aging, environmental changes and stress can cause a decline in dopamine levels, affecting cognitive performance, motivation and can even lead to a wide variety of health issues. Both of the nutrients in our brain-friendly formula maintain youthful dopamine levels in the brain by actively binding to enzymes that binds to and breaks down dopamine; by inhibiting these enzymes’ activity, there’s more dopamine available to the brain.

Phellodendron bark and MAO-B
Phellodendron amurense, commonly known as amur cork tree, has many health benefits, including neuroprotective properties. In a detailed 2016 screening study, Phellodendron amurense ranked as one of the most potent extracts for inhibiting the activity of monoamine oxidase-B (MAO-B), an enzyme involved in the metabolism of dopamine.1

Adenosylcobalamin and LRRK2
Adenosylcobalamin is a neurologically active form of vitamin B12—it can cross the brain-blood barrier and it’s more readily available to the brain. A 2019 study showed vitamin B12 also protects the brain from oxidative stress and that it modulates Leucine-Rich Repeat Kinase 2’s (LRRK2) activity, an enzyme that regulates dopamine levels.2-4 Add Dopamine Advantage to your daily regimen and “motivate” your brain to stay sharp and focused.